1. Mora-Ripoll R. Potential health benefits of simulated laughter: A narrative review of the literature and recommendations for future research. Comp Ther Medicine: 2011;19:170—177.
  2. Berk R, Martin R, Baird D, Nozik B. What everyone should know about humor and laughter. AlisoViejo: Association for Applied and Therapeutic Humor (AATH).; 2008

  3. Fry WF. The biology of humor. Humor: Int J Humor Res 1994;7:111—26.

  4. Sahakian A, Frishman WH. Humor and the cardiovascular system. Altern Ther Health Med 2007;13(4):56—8.

  5. Martin RA. Humor, laughter, and physical health: methodological issues and research findings. Pyschol Bull 2001;127:504—19.

  6. Martin RA, Lefcourt HM. Sense of humor and physical health: theoretical issues recent findings, and future directions. Humor 2004;17(1):1—20.

  7. Mora-Ripoll R, García-Rodera MC. El valor terapéutico de la risa en medicina. Med Clin (Barc) 2008;131(18):694—8.

  8. Martin RA. The psychology of humor: an integrative approach. London: Elsevier; 2006.

  9. Foley E, Matheis R, Schaefer C. Effects of forced laughter on mood. Psychol Rep 2002;90(1):184.

  10. Neuhoff CC, Schaefer C. Effects of laughing, smiling, and howling on mood. Psychol Rep 2002;91(3 Pt 2):1079—80.

  11. Szabo A, Ainsworth SE, Danks PK. Experimental comparison of the psychological benefits of aerobic exercise, humor, and music. Humor: Int J Humor Res 2005;18(3):235—46.

  12. Morgan AJ, Jorm AF. Self-help interventions for depressive disorders and depressive symptoms: a systematic review. Ann Gen Psychiatry 2008;7:13.

  13. Abel MH. Interaction of humor and gender in moderating relationships between stress and outcomes. J Psychol 1998;132 (May (3)):267—76.

  14. Kuiper NA, Martin RA. Laughter and stress in daily life: relation to positive and negative affect. Motivation Emotion 1998;22(2):133—53.

  15. Moore DB. Make them laugh. Therapeutic humor for patients with grief-related stress or anxiety. Adv Nurse Pract 2000;8(8):34—7.

  16. Gelkopf M, Sigal M, Kramer R. Therapeutic use of humor to improve social support in an institutionalized schizophrenic inpatient community. J Soc Psychol 1994;134(2): 175—82.

  17. Gelkopf M, Gonen B, Kurs R, Melamed Y, Bleich A. The effect of humorous movies on inpatients with chronic schizophrenia. J Nerv Ment Dis 2006;194(11):880—3.

  18. Abel MH. Humor, stress and coping strategies. Humor: Int J Humor Res 2002;15(4):365—81.

  19. Nezlek JB, Derks P. Use of humor as a coping mechanism, psychological adjustment, and social interaction. Humor: Int J Humor Res 2001;14(4):395—413.

  20. Arminen I, Halonen M. Laughing with and at patients: the role of laughter in confrontations in addiction group therapy. Qualitative Rep 2007;12(3):483—512.

  21. Ventis WL, Higbee G, Murdock SA. Using humor in systematic desensitization to reduce fear. J Gen Psychol 2001;128(2):241—53.

  22. Scholl JC, Ragan SL. The use of humor in promoting positive provider—patient interactions in a hospital rehabilitation unit. Health Commun 2003;15(3):319—30.

  23. Penson RT, Partridge RA, Rudd P, Seiden MV, Nelson JE, Chabner BA, et al. Laughter: the best medicine? Oncologist 2005;10:651—60.

  24. Evans W. Ottawa Lodges add humor to armamentarium in fight against cancer. Can Med Assoc J 1990;142:163—5.

  25. Erdman L. Laughter therapy for patients with cancer. Oncol Nurs Forum 1991;18:1359—63.

  26. Bellert JL. Humor, a therapeutic approach in Oncology nursing. Cancer Nurs 1989;12:65—70.

  27. Kimata H. Effect of humor on allergen-induced wheal reactions. JAMA 2001;285:738.

  28. Kimata H. Laughter elevates the levels of breast-milk melatonin. J Psychosom Res 2007;62(6):699—702.

  29. Bennett MP, Zeller JM, Rosenberg L, McCann J. The effect of mirthful laughter on stress and natural killer cell activity. Altern Ther Health Med 2003;9(2):38—45.

  30. McClelland R, Cheriff A. The immunoenhancing effects of humour on secretory IgA and resistance to respiratory infections. Psychol Health 1997;12(3):329—44.

  31. Bukutu C, Le C, Vohra S. Asthma: a review of complementary and alternative therapies. Pediatr Rev 2008;29(8):44—9.

  32. Boiten FA. The effects of emotional behaviour on components of the respiratory cycle. Biol Psychol 1998;49(1—2):29—51.

  33. Svebak S. Respiratory patterns as predictors of laughter. Psychophysiology  1975;12(1):62—5.

  34. Boone T, Hansen S, Erlandson A. Cardiovascular responses to laughter: a pilot project. Appl Nurs Res 2000;13(4):204—8.

  35. Nahas R. Complementary and alternative medicine approaches to blood pressure reduction. Can Fam Physician 2008;54:1529—33.

  36. Hayashi T, Urayama O, Hori M, Sakamoto S, Nasir UM, Iwanaga S, et al. Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes. J Psychosom Res 2007; 62(6): 703-6. 

  37. Sugawara J, Tarumi T, Tanaka H. Effect of mirthful laughter on vascular function. Am J Cardiol 2010;106(6):856—9.

  38. Yoshino S, Fujimori J, Kohda M. Effects of mirthful laughter on neuroendocrine and immune systems in patients with rheumatoid arthritis. J Rheumatol 1996;23(4):793—4.

  39. Basmajian JV. The elixir of laughter in rehabilitation. Arch Phys Med Rehabil 1998;79:1597.

  40. Schmitt N. Patients’ perception of laughter in a rehabilitation hospital. Rehabil Nurs 1990;15(3):143—6.

  41. Saper B. The therapeutic use of humor for psychiatric disturbances of adolescents and adults. Psychiatr Q 1990;61:261—72.

  42. Gelkopf M, Kreitler S, Sigal M. Laughter in a psychiatric ward. Somatic, emotional, social, and clinical influences on schizophrenic patients. J Nerv Ment Dis 1993;181:283—9.

  43. van Alphen PJ. Humor as diagnostic and therapeutic tool in psychiatry. Laughter is healthy. TVZ 1997;107(22):6

  44. Seaward BL. Humor’s healing potential. Health Prog 1992;73(3):66—70. 

  45. Krack P, Kumar R, Ardouin C, Dowsey PL, McVicker JM, Benabid AL, et al. Mirthful laughter induced by subthalamic nucleus stimulation. Mov Disord 2001;16(5):867—75. 

  46. Fried I, Wilson CI, MacDonald KA, Behnke EJ. Electric current stimulates laughter. Nature 1998;391:650.

  47. Taber KH, Redden M, Hurley RA. Functional anatomy of humor: positive affect and chronic mental illness. J Neuropsychiatry Clin Neurosci 2007;19(4):358—62.

  48. Meyer M, Baumann S, Wildgruber D, Alter K. How the brain laughs. Comparative evidence from behavioural, electrophysiological and neuroimaging studies in human and monkey. Behav Brain Res 2007;182(2):245—60.

  49. Kawakami K, Takai-Kawakami K, Tomonaga M, Suzuki J, Kusaka T, Okai T. Origins of smile and laughter: a preliminary study. Early Hum Dev 2006;82:61—6.

  50. Pearce JMS. Some neurological aspects of laughter. Eur Neurol 2004;52:169—71.

  51. Wild B, Rodden FA, Grodd W, Ruch W. Neural correlates of laughter and humor. Brain 2003;126:2121—38.

  52. Luschei ES, Ramig LO, Finnegan EM, Baker KK, Smith ME. Patterns of laryngeal electromyography and the activity of the respiratory system during spontaneous laughter. J Neurophysiol 2006;96:442—50.

  53. Bea JA, Marijuán PC. The informational patterns of laughter. Entropy 2003;5:205—13.

  54. Kohler KJ. Speech—smile, speech—laughter, laughter and their sequencing in dialogic interaction. Phonetica 2008;65:1—18.

  55. Bachorowski JA, Smoski MJ, Owren MJ. The acoustic features of human laughter. J Acoust Soc Am 2001;110(3):1581—97.

  56. Bachorowski JA, Owren MJ. Not all laughs are alike: voiced but not unvoiced laughter readily elicits positive affect. Psychol Sci 2001;12(3):252—7.

  57. Williams H. Humor and healing: therapeutic effects in geriatrics. Gerontion 1986;1:14—7.

  58. O’Brien ME. Integrative geriatrics. Combining traditional and alternative medicine. N C Med J 1996;57(6):364—7.

  59. Tennant KF. Laugh it off. The effect of humor on the wellbeing of the older adult. J Gerontol Nurs 1990;16(12):11—7. 

  60. Evans S, Tsao JC, Zeltzer LK. Complementary and alternative medicine for acute procedural pain in children. Altern Ther Health Med 2008;14(5):52—6.

  61. Henderson SW, Rosario K. But seriously: clowning in children’s mental health. J Am Acad Child Adolesc Psychiatry 2008;47(9):983—6.

  62. Reddy V, Williams E, Vaughan A. Sharing humour and laughter in autism and Down’s syndrome. Br J Psychol 2002;93(Pt 2):219—42. 

  63. Beddoe AE, Lee KA. Mind—body interventions during pregnancy. JOGNN 2008;37:165—75. 

  64. Cantó MA, Quiles JM, Vallejo OG, Pruneda RR, Morote JS, Pi˜nera MJ, et al. Evaluation of the effect of hospital clown’s performance about anxiety in children subjected to surgical intervention. Cir Pediatr 2008;21(4):195—8.

  65. Robinson V. The purpose and function of humor in OR nursing. Todays OR Nurse 1993;15(6):7—12.

  66. Liechty RD. Humor and the surgeon. Arch Surg 1987;122(5):519—22. 

  67. Morse DR. Use of humor to reduce stress and pain and enhance healing in the dental setting. J N J Dent Assoc 2007;78(4):32—6.

  68. Wilde JA. Laughing all the way. Dent Today 1998;17(12):38—41.

  69. Davis DM, Fiske J, Scott B, Radford DR. The emotional effects of tooth loss in a group of partially dentate people: a quantitative study. Eur J Prosthodont Restor Dent 2001;9(June(2)):53—7. 

  70. McCreaddie M, Wiggins S. The purpose and function of humour in health, health care and nursing: a narrative review. J Adv Nurs 2008;61(6):584—95.

  71. MacDonald CM. A chuckle a day keeps the doctor away: therapeutic humor and laughter. J Psychosoc Nurs Ment Health Serv 2004;42(3):18—25.

  72. Mathew FM. Laughter is the best medicine: the value of humour in current nursing practice. Nurs J India 2003;94(7):146—7.

  73. Astedt-Kurki P, Isola A. Humour between nurse and patient, and among staff: analysis of nurses’ diaries. J Adv Nurs 2001;35(3):452—8.

  74. Bakerman HM. Humour as a nursing intervention. Axone 1997;18(3):56—61.

  75. Herth KA. Laughter. A nursing Rx. Am J Nurs 1984;84(8):991—2. 

  76. Berry S. Humor me on this one. The healing role of humor in EMS. JEMS 2003;28(11):66—79.

  77. Ratzan RM. Laughter in the temple of pain and illness. Emerg Med 1996;14(1):92—5.

  78. Leiber DB. Laughter and humor in critical care. Dimens Crit Care Nurs 1976;5:162—70.

  79. Borod M. SMILES — toward a better laughter life: a model for introducing humor in the palliative care setting. J Cancer Educ 2006;21(1):30—4.

  80. Dean RA, Gregory DM. Humor and laughter in palliative care: an ethnographic investigation. Palliat Support Care 2004;2(2):139—48.

  81. Dean RA. Humor and laughter in palliative care. J Palliat Care 1997;13:34—9.

  82. Herth K. Contributions of humor as perceived by the terminally ill. Am J Hosp Care 1990;7:36—40.

  83. Graham LL, Cates JA. Responding to the needs of the terminally ill through laughter and play. Am J Hosp Care 1989;6(1):29—30. 

  84. Vagnoli L, Caprilli S, Robiglio A, Messeri A. Clown doctors as a treatment for preoperative anxiety in children: a randomized prospective study. Pediatrics 2005;116:563—7.

  85. Parish AB. It only hurts when I don’t laugh. Am J Nurs 1994;94(8):46—7.

  86. Strickland D. Overcome terminal seriousness: let go laugh, and lighten up. Semin Perioper Nurs 1999;8:53—9. 

  87. Hunter P. Humor therapy in home care, September. Caring Magazine; 1997. pp. 56—57. 

  88. Ruiz Gómez MC, Rojo Pascual C, Ferrer Pascual MA, Jiménez Navascués L, Ballesteros García M. Terapias complementarias en los cuidados. Humor y risoterapia. Index Enferm (Gran) 2005;48—49:37—41.

  89. Harries G. Use of humour in patient care. Br J Nurs 1995;4(17):984—6.

  90. Mallet J. Use of humour and laughter in patient care. Br J Nurs 1993;2:172—5.

  91. Granek-Catarivas M, Goldstein-Ferber S, Azuri Y, Vinker S, Kahan E. Use of humour in primary care: different perceptions among patients and physicians. Postgrad Med 2005;81:126—30. 

  92. Fowler JH, Christakis NA. Dynamic spread of happiness in a large social network: longitudinal analysis over 20 years in the Framingham Heart Study. BMJ 2008;337:a2338.

  93. Chapell M, Batten M, Brown J, Gonzalez E, Herquet G, Massar C, et al. Frequency of public laughter in relation to sex, age, ethnicity, and social context. Percept Mot Skills 2002;95(3 Pt 1):746.

  94. Demmer C. A survey of complementary therapy services offered by hospices. J Palliat Med 2004;7(4):510—6.

  95. Astin JA, Shapiro SL, Eisenberg DM, Forys KL. Mind—body medicine: state of the science, implications for practice. J Am Board Fam Pract 2003;16:131—47.

  96. Zagvazdin Y. Movies and emotional engagement: laughing matters in lecturing. Fam Med 2007;39(4):245—7.

  97. Park CM. Diversity, the individual, and proof of efficacy: complementary and alternative medicine in medical education. Am J Public Health 2002;92(10):1568—72.

  98. Tiralongo E, Wallis M. Integrating complementary and alternative medicine education into the pharmacy curriculum. Am J Pharm Educ 2008;72(4):74.